Multiple Myeloma | Oncology Today with Dr Neil Love: Emerging Role of CELMoDs (Cereblon E3 Ligase Modulators) and Other Novel Approaches to Targeting Protein Degradation Pathways in Multiple Myeloma (Companion Faculty Lecture)
Update: 2023-09-28
Description
Featuring a slide presentation and related discussion from Dr Paul G Richardson, including the following topics:
- Biologic rationale for targeting protein degradation pathways as a therapeutic approach in multiple myeloma (MM); mechanism of action of CELMoDs (0:00 )
- Published efficacy and safety findings with iberdomide-containing combination regimens from the Phase I/II CC-220-MM-001 study (6:30 )
- Emerging data with mezigdomide/dexamethasone for relapsed/refractory MM (13:22 )
- Early results with and ongoing investigations of mezigdomide/dexamethasone in combination with a proteasome inhibitor (29:54 )
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